Howdy @krm ! The Triple Bypass in on my "list." While I can't speak from experience with that particular ride, my first tip for long rides is always some type of chamois cream. https://www.rei.com/search?q=chamois+cream I've used a few different ones over the years and each person you talk to will have a different "favorite." I know we also have many employees in our stores in Colorado who have done the ride. Don't hesitate to drop into one of our stores or give us a call! I'll be following this conversation to see if others have great ideas I can incoporate into my long-distance rides. Have a great time!
Thanks, JasonO! Good point! Yesterday, I rode 128 miles in 95 degrees, 105 heat index, using Chamois Butt'r. Happy to say, no sore spots or chafing. Plenty of sweating, though!