Kersage to Mammoth is a section I'm considering since I came out there last year after hiking from Horseshoe via Whitney.  But...going over Kearsarge pass with a full load on the first day is bit of the schelp.  Also that section to Mammoth is a heavy carry.  The resupplies at MTR and VVR are 7-8 days on at about 12 miles a day over several high (~12000ft) passes so you have to keep moving and it's hard work.  I think I want something a bit more relaxed.  Maybe a loop out from Mammoth or VVR or something in Yosemite, perhaps the Grand Canyon of the Tuolumne.  Will probably do something in Desolation Wilderness.