As others have said sleeping system, shelter, and pack are great places to start.  I did exactly that withmy36 lb load and brought it down to 26. 

The next thing to consider is your kitchen.  It is easy to have too much kitchen stuff.  Your decision about water filtration, chemicals, UV, or boiling and whether you use alcohol, butane, or wood all involve trade offs that you should consider.

Finally, avoid hauling extra trinkets and electronic gadgets.  Your phone, camera, gps, spare batteries, charging equipment, spare flashlight are heavy and they add up fast.  An extra knife isn’t required, etc.  Multiuse items are the key and your contingency items should find other useful roles.